TABLE 1.
Study Participants (survivors with 18-mo and 6- to 7-y assessments), N = 110 | Excluded (survivors without both assessments), N = 30 | |
---|---|---|
Maternal characteristics, (%) | ||
Race, n* | ||
Black | 38 (35) | 9 (30) |
White | 45 (41) | 6 (20) |
Other | 27 (25) | 15 (50) |
Maternal age, y | 26.8 ± 5.8 | 27.3 ± 6.5 |
Married, n | 65 (61) | 14 (48) |
Maternal education less than high school (at birth) | 29 (35) | 9 (38) |
Maternal education less than high school (at 18 mo) | 27 (26) | 8 (32) |
Medicaid (at 18 mo) | 55 (50) | 16 (64) |
Prenatal care | 103 (94) | 29 (97) |
Gravida, median n | 2 | 2 |
Parity, median n | 2 | 1.5 |
Complications of pregnancy, n | ||
Chronic hypertension | 18 (16) | 4 (13) |
Antepartum hemorrhage | 20 (18) | 2 (7) |
Thyroid disease | 0 (0) | 0 (0) |
Diabetes | 10 (9) | 4 (13) |
Intrapartum complications, n | ||
Fetal heart decelerations | 82 (75) | 24 (80) |
Cord prolapse | 20 (18) | 5 (17) |
Uterine rupture | 17 (15) | 3 (10) |
Maternal pyrexia | 11 (10) | 4 (13) |
Shoulder dystocia | 14 (13) | 3 (14) |
Maternal hemorrhage | 9 (8) | 0 (0) |
Labor, h | 13.4 ± 10.1 | 11.7 ± 8.4 |
Rupture of membrane, h | 6.5 ± 11.7 | 5.5 ± 6.8 |
Emergency cesarean delivery, n | 79 (72) | 21 (70) |
Neonatal characteristics | ||
Age at randomization, h | 4.4 ± 1.3 | 4.4 ± 1.1 |
Transferred from birth hospital, n | 48 (44) | 11 (37) |
Male gender, n | 61 (55) | 17 (57) |
Apgar score ≤5, n | ||
At 5 min | 97 (88) | 25 (86) |
At 10 min | 76 (76) | 18 (69) |
Birth wt, g | 3359 ± 589 | 3458 ± 829 |
Length, cm | 50.8 ± 3.0 | 51.5 ± 2.9 |
Head circumference, cm | 34.1 ± 1.6 | 33.7 ± 2.3 |
Intubation in delivery room, n | 101 (92) | 28 (93) |
Continued respiratory support at 10 min, n | 100 (91) | 28 (93) |
Time to spontaneous respiration ≥10 min, n | 66 (62) | 14 (54) |
Cord blood | ||
pH | 6.9 ± 0.2 | 6.9 ± 0.2 |
Base deficit, mmol/L | 18.2 ± 7.3 | 17.5 ± 6.6 |
Seizures, n | 51 (46) | 9 (30) |
Moderate encephalopathy, n | 86 (78) | 22 (76) |
Severe encephalopathy, n | 24 (22) | 7 (24) |
Inotropic support, n | 34 (31) | 11 (37) |
Anticonvulsants, n | 47 (47) | 10 (36) |
P < .05.