Table 2.
Correlation coefficients and their significance (P) are shown for the expression of cell growth and differentiation-related genes in relation to BMD in postmenopausal osteoporotic women.
| mTOR | TGFβ1 | RUNX2 | TNFα | IL-1β | Caspase-3 | |
|---|---|---|---|---|---|---|
| RUNX2 | 0.768 | 0.768 | ||||
| (P < 0.001) | (P < 0.001) | |||||
|
| ||||||
| TNFα | 0.664 | 0.504 | ||||
| (P = 0.005) | (P = 0.03) | |||||
|
| ||||||
| IL-1β | 0.424 | 0.696 | 0.496 | 0.494 | ||
| (P = 0.06) | (P < 0.001) | (P = 0.01) | (P = 0.03) | |||
|
| ||||||
| Caspase-3 | 0.666 | 0.481 | 0.519 | 0.867 | 0.637 | |
| (P = 0.003) | (P = 0.03) | (P = 0.01) | (P < 0.001) | (P = 0.002) | ||
|
| ||||||
| p21 | 0.580 | 0.868 | 0.680 | 0.715 | 0.675 | 0.715 |
| (P = 0.009) | (P < 0.001) | (P = 0.001) | (P = 0.002) | (P = 0.001) | (P = 0.001) | |
|
| ||||||
| TGFβ1 | 0.632 | |||||
| P = 0.004 | ||||||
|
| ||||||
| Cathepsin K | 0.542 | 0.516 | ||||
| (P = 0.03) | (P = 0.07) | |||||
|
| ||||||
| Lumbar spine | ||||||
|
| ||||||
| Femoral neck | ||||||
|
| ||||||
| Trochanter | 0.548 | |||||
| (P = 0.01) | ||||||
|
| ||||||
| Ward triangle | 0.516 | |||||
| (P = 0.02) | ||||||
|
| ||||||
| Total femur | 0.524 | 0.605 | ||||
| (P = 0.02) | (P = 0.005) | |||||