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. Author manuscript; available in PMC: 2016 Feb 19.
Published in final edited form as: Mol Cell. 2015 Feb 19;57(4):595–606. doi: 10.1016/j.molcel.2015.01.022

Figure 4. Rmi1 stimulates D-loop dissolution by Top3.

Figure 4

A, Reaction scheme for Rmi1-stimulated reactions. B, D-loop dissolution by Top3 or Top3-Rmi1 (0, 2, 5, 10, 20 nM). C, Quantitation of D-loops. Shown are normalized means ± standard deviations of three independent experiments. The absolute values corresponding to maximal D-loop levels are Top3: 21.1%, Top3-Rmi1: 18.7%. D, Reaction scheme with tailed 95-mer. E, D-loop dissolution time course by 2 nM Top3-Rmi1. F, Quantitation of D-loops. Shown are means ± standard deviations of three independent experiments.