Table 3.
Outcome | Overall |
Male |
Female |
||||||
---|---|---|---|---|---|---|---|---|---|
Treated | Untreated | Adjusted RR (95% CI)* | Treated | Untreated | Adjusted RR (95% CI)* | Treated | Untreated | Adjusted RR (95% CI)* | |
BMI ≥95th percentile for age and sex | 55 (20.8) | 54 (22.9) | 0.94 (0.68–1.28) | 35 (25.0) | 30 (24.8) | 1.04 (0.70–1.55) | 20 (16.1) | 24 (20.9) | 0.79 (0.48–1.33) |
BMI ≥85th percentile for age and sex | 86 (32.6) | 91 (38.6) | 0.88 (0.71–1.10) | 49 (35.0) | 46 (38.0) | 0.94 (0.70–1.27) | 37 (29.8) | 45 (39.1) | 0.81 (0.59–1.13) |
Waist circumference >90th percentile for age, sex, and race/ethnicity | 31 (11.7) | 27 (11.4) | 1.05 (0.65–1.69) | 18 (12.9) | 15 (12.4) | 1.06 (0.56–2.00) | 13 (10.5) | 12 (10.4) | 1.02 (0.49–2.13) |
Impaired fasting glucose ≥100 mg/dL† | 12 (5.7) | 13 (7.2) | 0.76 (0.36–1.62) | 9 (8.4) | 2 (2.2) | 3.50 (0.78–15.7) | 3 (2.9) | 11 (12.1) | 0.24 (0.07–0.82)‡ |
Elevated triglycerides ≥100 mg/dL 4–9 years; ≥130 mg/dL 10 years | 38 (18.2) | 29 (16.0) | 1.11 (0.71–1.72) | 18 (16.8) | 11 (12.2) | 1.31 (0.66–2.62) | 20 (19.6) | 18 (19.8) | 0.99 (0.56–1.75) |
Low HDL cholesterol <40 mg/dL | 27 (13.0) | 22 (12.2) | 1.03 (0.61–1.76) | 13 (12.2) | 8 (8.9) | 1.31 (0.57–3.00) | 14 (13.9) | 14 (15.4) | 0.88 (0.45–1.73) |
Hypertension ≥95th percentile or age, sex, and height | 30 (11.5) | 23 (9.8) | 1.23 (0.74–2.05) | 20 (14.7) | 13 (10.7) | 1.41 (0.74–2.71) | 10 (8.1) | 10 (8.7) | 0.97 (0.42–2.23) |
Data are n (%) unless otherwise indicated. RR, relative risk.
All models adjusted for race/ethnicity and log maternal baseline BMI, except waist circumference >90th percentile for age, sex, and race/ethnicity was adjusted only for log maternal baseline BMI. The data presented by child sex are based on multivariable adjusted models that included treatment group, sex, and a treatment group-by-sex interaction term.
P = 0.007 for interaction between treatment group and sex.
P = 0.02.