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. Author manuscript; available in PMC: 2015 Jul 1.
Published in final edited form as: Stroke. 2014 Dec 4;46(1):102–107. doi: 10.1161/STROKEAHA.114.007036

Table 1.

Systematic review data assessing how characteristics of arterial obstruction (location and extent) and time from stroke onset affect hyperdense artery sign (HAS) prevalence

Author Year Angiography n Location of Arterial Obstruction Number of Obstructed Arterial Segments Time from Stroke Onset to Scan (minutes)
Proximal Distal 1 ≥2 ≤180 ≥180
Assouline25 2005 39 8/16(50) 6/7(86) 11/17(65) 4/8(50)
Barber22 2004 100 7/25(28) 11/24(46)
Bastianello6 1991 36 12/17(71) 6/13(46)
Flacke19 2000 23 6/10(60) 0/10(0)
Froehler28 * 2013 67 15/20(75) 23/43(53)
Garg7 2004 65 1/8(13) 8/57(14)
Kim23 2005 51 11/38(29) 7/31(23)
Kim26 2008 78 36/56(64) 10/22(45)
Koga20 2003 105 21/63(33) 6/38(16)
Tomsick15 1990 20 4/9(44) 2/7(29) 3/10(30) 3/6(50)
Tomsick16 1992 38 7/14(50) 5/12(42) 8/22(36) 6/7(86)
von Kummer18 1994 53 20/43(47) 5/10(50)
Wolpert17 1993 60 12/43(28) 4/17(24)
IST-38 2012 273 50/91(55) 12/23(52) 34/66(52) 28/48(58) 34/151(23) 35/122(29)
TOTAL 189/402(47) 92/247(37) 56/115(49) 41/69(59) 55/202(27) 48/189(25)
p-value for difference 0.015 0.160 0.682

Results represent number of HAS within each total (%). Data were only included when results were available for both sides of the equation (e.g. proximal and distal); 3 articles with incomplete data are not included.

Unless otherwise stated, proximal arterial locations include internal carotid artery, main-stem of the middle cerebral artery (MCA), vertebral and basilar arteries. Distal arterial locations include sylvian branches of the MCA, and anterior and posterior cerebral arteries.

*

Proximal and distal arteries are defined here as internal carotid and middle cerebral arteries, respectively.

Thick-slice (5mm) CT data are presented here. Thin-slice data are also available.