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. Author manuscript; available in PMC: 2015 Jul 1.
Published in final edited form as: Nat Neurosci. 2014 Dec 15;18(1):46–55. doi: 10.1038/nn.3896

Figure 6. Transcription factor expression patterns in d-Ipc neuroblasts.

Figure 6

(a) p-Ipc neuroepithelial cells (arrowhead) adjacent to cell streams express Lethal of scute (L’sc, red). (b,c) Deadpan-positive (Dpn+, blue) d-Ipc neuroblasts (Nb) sequentially express Asense (Ase, red, arrowheads, b), Atonal (Ato, red, arrows, c) and Dachshund (Dac, green, arrows b,c), and solely Dac (double arrowheads, c). (d,e) Dichaete (D, blue) shows strong overlap with Ase (red, arrowheads, d), and weak or no overlap with Ato (red) and Dac (green) in neuroblasts (arrows, e). (f) Progenitors (arrows) and lower d-Ipc neuroblasts (asterisk) express D (blue). Tailless (Tll, red) is expressed in p-Ipc neuroepithelial cells (double arrowheads), upper d-Ipc neuroblasts (arrowheads), ganglion mother cells (Gmc), and young distal cells (dc) and lobula plate neurons (lopn). D and Tll overlap in central neuroblasts (small arrows). (g) The wild type (wt) MARCM clone shows that neuroblasts in the lower d-Ipc give rise to Gmcs orientated towards the lamina (la, arrows), and where distal cells are found. Asterisk indicates an independent lamina glia clone. (h) The clone shows labeling of distal cells, and Ase-negative neuroblasts in the upper d-Ipc, that produce lobula plate neurons. (i) GFP driven by decapentaplegic (dpp)-Gal4 is present in a subset of neuroblasts and persists in both distal cell and lobula plate neuron populations. (j) Summary of expression patterns. For genotypes and sample numbers, see Supplementary Table 1. Scale bars, 50 μm.