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. Author manuscript; available in PMC: 2015 Aug 12.
Published in final edited form as: Nature. 2015 Feb 12;518(7538):187–196. doi: 10.1038/nature14132

Extended Data Figure 5. Regulatory element overlap with WHRadjBMI-associated loci.

Extended Data Figure 5

a, Five variants associated with waist-hip ratio adjusted for body mass index (WHRadjBMI) and located ~77 kb upstream of the first CALCRL transcription start site overlap regions with genomic evidence of regulatory activity in endothelial cells. b, Five WHRadjBMI variants, including rs8817452, in a 1.1 kb region (box) ~250 kb downstream of the first LEKR1 transcription start site overlap evidence of active enhancer activity in adipose nuclei. Signal enrichment tracks are from the ENCODE Integrative Analysis and the Roadmap Epigenomics track hubs on the UCSC Genome Browser. Transcripts are from the GENCODE basic annotation.