Skip to main content
. 2015 Feb 3;7(1):5. doi: 10.1186/s13195-014-0081-2

Figure 4.

Figure 4

Mean MMSE change in subgroups of improved and less-improved by 5 mg (FAS, DON5-DON10 group). MMSE, Mini-Mental State Examination; FAS, full analysis set; LOCF, last observation carried forward. (a)The cognitively improved by 5 mg is defined as a patient with 3 points or more improvement in the MMSE score at Week 24, and the less-improved as a patient with fewer than 3 points improvement. (b)Treatment with 10 mg started at Week 24 (dose decrease to 5 mg was allowed). *P < 0.05 (paired t test versus Week 24).