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. 2015 Feb 3;7(1):5. doi: 10.1186/s13195-014-0081-2

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© Mori et al.; licensee BioMed Central. 2015

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Mean change in ZBI from baseline (FAS). ZBI, Zarit Caregiver Burden Interview; FAS, full analysis set. ^(a)PLA-DON10 group started treatment with 3 mg at Week 16, and the dose was increased to 5 mg at Week 18. ^(b)PLA-DON10 and DON5-DON10 groups started treatment at 10 mg from Week 24 (dose decrease to 5 mg was allowed). *P < 0.05 (paired t test).