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. Author manuscript; available in PMC: 2015 Apr 1.
Published in final edited form as: Exp Hematol. 2014 Jan 6;42(4):282–293.e4. doi: 10.1016/j.exphem.2013.12.007

Figure 4. Effects of targeted drugs on SDF-1α-induced migration of EOL-1 cells.

Figure 4

EOL-1 cells were pre-incubated in control medium (Co) or in medium containing ponatinib, sorafenib, masitinib, nilotinib, imatinib, or dasatinib (each 10 or 100 nM) at 37°C for 1 hour. Then, migration of cells against SDF-1α (30 ng/ml) was determined in a double-chamber chemotaxis assay (4 hours) as described in the text. Numbers of viable migrated cells are expressed as percent of total (100% input) cells. Results represent the mean±S.D. of 4 independent experiments. Asterisk: p<0.05.