Table 1. Characteristics of Study Participants.
Characteristic | Noncarriers (5,060) | BRCA1 mutation (1,058) | BRCA2 mutation (438) | |||
---|---|---|---|---|---|---|
|
||||||
N | % | N | % | N | % | |
Histology | ||||||
Serous | 3,052 | 65 | 553 | 73 | 254 | 77 |
Mucinous | 271 | 6 | 5 | 0.7 | 1 | 0.3 |
Endometrioid | 587 | 12 | 91 | 12 | 27 | 8 |
Clear cell | 306 | 6 | 14 | 2 | 7 | 2 |
Mixed cell | 150 | 3 | 8 | 1 | 7 | 2 |
Other | 345 | 7 | 82 | 11 | 32 | 10 |
Unknown | 349 | - | 305 | - | 110 | - |
Grade | ||||||
Low | 491 | 11 | 19 | 2 | 13 | 4 |
High | 3,778 | 88 | 801 | 98 | 331 | 96 |
Unknown | 791 | - | 238 | - | 94 | - |
Stage | ||||||
Localized | 967 | 21 | 97 | 12 | 29 | 8 |
Regional | 818 | 18 | 101 | 12 | 55 | 15 |
Distant | 2808 | 61 | 622 | 76 | 274 | 76 |
Unknown | 467 | - | 238 | - | 80 | - |
Age at EOC diagnosis, mean (SD), year | 59(11) | 52 (10) | 59 (10) |
The cases with unknown histology, grade and stage were not included in the calculation of proportions.