Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2014 Dec 16;3(6):e001232. doi: 10.1161/JAHA.114.001232

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2014 The Authors. Published on behalf of the American Heart Association, Inc., by Wiley Blackwell.

This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.

PMC Copyright notice

Figure 8. — IgG and ApoB immune complexes are higher in DKO plasma. IgG levels in peripheral blood were compared at 15 (chow diet) and 26 weeks (15 weeks chow, 11 weeks high‐fat diet). In DKO plasma, all classes of IgG, as well as the concentrations of oxLDL and ApoB‐IgG immune complexes, were elevated, compared to Apoe^−/−. For immune complex levels, the assay controls contained either no serum or serum from 26‐week C57/BL6 mice on chow diet. The IC concentration was significantly higher in DKO, compared to Apoe^−/−, plasma. Each symbol represents 1 animal. Data are presented as mean±SEM for 12 (Apoe^−/−) and 10 (DKO) animals. Significance was determined by independent sample t test. *P<0.05; **P<0.01; **P<0.001. Apo indicates apolipoprotein; DKO, double knockout; IC, immune complexes; IgG, immunoglobulin G; oxLDL, oxidized low‐density lipoprotein.