. 2014 Dec 16;3(6):e001232. doi: 10.1161/JAHA.114.001232

Table 3.

Cell Composition in the Lymph Nodes of Apoe^−/− and DKO Mice

Cervical Lymph Nodes	Apoe^−/− (n=8)	DKO (n=7)
B220⁺/CD3⁻	39.5±3.1	43.9±4.5
CD3⁺/B220⁻	38.0±4.5	29.6±2.5
CD4⁺/CD8⁻^*	49.8±0.8	56.6±2.3^*
CD8⁺/CD4⁻^*	38.0±1.9	28.8±1.0^**
CD11c⁺/CD11b⁺/CD3⁻/B220⁻	0.48±0.1	1.3±0.4^*
CD11c⁻/CD11b⁺/CD3⁻/B220⁻/SSC^hi	0.5±0.1	0.6±0.1
CD11c⁻/CD11b⁺/CD3⁻/B220⁻/SSC^low	0.5±0.1	0.9±0.1^*

Cervical lymph nodes draining the casted artery were removed at 26 weeks and the cells analyzed by flow cytometry. Data are presented as mean±SEM percent of the total cell population and analyzed by independent sample t test. Apo indicates apolipoprotein; DKO, double knockout.

*P<0.05; **P<0.01. CD4⁺ T cells were increased with a corresponding decrease in CD8⁺ cells. Myeloid‐derived dendritic cells were also significantly elevated in DKO lymph nodes.

Percent of CD3⁺ population.