Table 3.
Associations of Parathyroid Hormone (PTH) and 25‐Hydroxyvitamin D (25[OH]D) With Left Ventricular Mass (LVM) in the Multi‐Ethnic Study of Atherosclerosis (N=4763)
| Covariate | N | Unadjusted Mean (SD), g | Difference in LVM (95% CI), g | ||
|---|---|---|---|---|---|
| Model 1 | Model 2 | Model 3 | |||
| PTH | |||||
| <65 pg/mL | 4244 | 144 (38.8) | 0 (Ref) | 0 (Ref) | 0 (Ref) |
| ≥65 pg/mL | 519 | 155 (42.7) | 11.1 (8, 14.2) | 4.1 (1.5, 6.7) | 5.3 (2.6, 7.9) |
| 25(OH)D | |||||
| ≥30 ng/mL | 1631 | 139.5 (37.7) | Ref | Ref | Ref |
| 20 to 29 ng/mL | 1663 | 145.7 (39.1) | 2.8 (0.8, 4.8) | −0.8 (−2.4, 0.9) | −1.3 (−3, 0.4) |
| <20 ng/mL | 1469 | 151 (40.7) | 4.2 (1.9, 6.5) | −1.8 (−3.7, 0.1) | −2.8 (−4.9, −0.8) |
Model 1: adjusted for age, sex, race/ethnicity, education. Model 2: Model 1+height, weight, smoking, physical activity level, diabetes, eGFR, urine ACR, systolic blood pressure, antihypertensive medications. Model 3: Model 2 +calcium, phosphorus, FGF‐23, PTH/25(OH)D (alternative measure to the predictor). ACR indicates albumin to creatinine ratio; eGFR, estimated glomerular filtration rate.