Table 4.
Terminal Negativity of P Wave in V1 and Fully Adjusted Risk of SCD Across Subgroups
| HR (95%CI) | P Value | |
|---|---|---|
| Male (199 SCDs/6865) | 2.36 (1.27 to 4.38) | 0.007 |
| Female (112 SCDs/8511) | 3.37 (1.44 to 7.86) | 0.005 |
| Interaction | 0.375 | |
| Age ≥55 y (207 SCDs/7244) | 2.42 (1.28 to 4.57) | 0.006 |
| Age<55 y (104 SCDs/8132) | 2.84 (1.21 to 6.67) | 0.017 |
| Interaction | 0.929 | |
| White (177 SCDs/11248) | 1.82 (0.87 to 3.80) | 0.111 |
| Black (134 SCDs/4128) | 3.33 (1.67 to 6.65) | 0.001 |
| Interaction | 0.716 | |
| CVD Yes (129 SCDs/2098) | 2.06 (1.07 to 3.96) | 0.030 |
| CVD‐Healthy (182 SCDs/13278) | 3.59 (1.62 to 7.97) | 0.002 |
| Interaction | 0.801 | |
| Diabetes Yes (102 SCDs/1494) | 3.93 (1.57 to 9.82) | 0.003 |
| Diabetes No (208 SCDs/13766) | 1.85 (0.99 to 3.46) | 0.056 |
| Interaction | 0.659 | |
| Hypertension Yes (150 SCDs/3861) | 2.71 (1.35 to 5.44) | 0.005 |
| Hypertension No (159 SCDs/11436) | 2.67 (1.28 to 5.65) | 0.010 |
| Interaction | 0.326 | |
| ECG LVH Yes (52 SCDs/863) | 4.32 (1.56 to 11.92) | 0.005 |
| ECG LVH No (259 SCDs/14513) | 2.10 (1.13 to 3.93) | 0.019 |
| Interaction | 0.192 | |
| P duration >110 ms (155 SCDs/5955) | 2.02 (1.06 to 3.84) | 0.034 |
| P duration ≤110 ms (156 SCDs/9421) | 4.65 (2.10 to 10.28) | <0.0001 |
| Interaction | 0.064 | |
| IACB third degree Yes# (4 SCDs/85) | 6.62 (0.62 to 70.42) | 0.117 |
| IACB third degree No (307 SCDs/15291) | 2.95 (1.79 to 4.85) | <0.0001 |
| Interaction | 0.821 |
CVD is defined as a presence of either coronary heart disease, or heart failure, or stroke, or QRS duration ≥120 ms. Left ventricular hypertrophy defined as sex‐specific Cornell product >2440 mm×ms. IACB, interatrial conduction block. # model was adjusted by sex, race, age, and CVD only. CHD indicates coronary heart disease; CVD, cardiovascular disease; LVH, left ventricular hypertrophy SCD, sudden cardiac death.