. 2014 Nov 10;3(6):e001398. doi: 10.1161/JAHA.114.001398

Table 8.

Association Results of the Top SNP Associated With RHTN in INVEST‐GENES, ATP2B1 rs12817819, by Gender in INVEST‐GENES

Gender	Minor Allele	Race	n	MAF	OR (95% CI)	P Value	Meta‐Analysis OR (95% CI)	Meta‐Analysis P Value
Males	A	EA	501	0.124	1.70 (1.14 to 2.55)	0.0093	1.77 (1.44 to 2.10)	6.16E‐04
Males	A	Hispanic	302	0.119	1.91 (1.08 to 3.40)	0.0254	1.77 (1.44 to 2.10)	6.16E‐04
Females	A	EA	403	0.137	1.41 (0.91 to 2.19)	0.1226	1.56 (1.26 to 1.86)	3.53E‐03
Females	A	Hispanic	535	0.108	1.70 (1.13 to 2.57)	0.0116	1.56 (1.26 to 1.86)	3.53E‐03

EA indicates European American; INVEST‐GENES, INternational VErapamil SR Trandolapril Study–GENEtic Substudy; MAF, minor allele frequency; n, number; odds ratio; RHTN, resistant hypertension; SNP, single‐nucleotide polymorphism.