Table 7.

Summary of 2010 ARVC Task Force Criteria for the Study Population

ARVC Task Force Criteria	Homozygotes (n=11)	Heterozygotes (n=28)	Mutation‐Negatives (n=22)	P Value
Repolarization major, n (%)	11/11 (100)	0/25 (0)	0/21 (0)	<0.001
Repolarization minor, n (%)	0/11 (0)	1/25 (4)	0/21 (0)	1.0
Depolarization major, n (%)	3/11 (27)	0/25 (0)	0/21 (0)	0.006
Depolarization minor, n (%)	9/11 (82)	5/25 (20)	1/21 (5)	<0.001
Arrhythmia major, n (%)	1/10 (10)	0/26 (0)	0/7 (0)	0.395
Arrhythmia minor, n (%)	9/10 (90)	1/26 (4)	1/7 (14)	<0.001
CMR major, n (%)	3/11 (27)	2/24 (8)	0/6 (0)	0.311
CMR minor, n (%)	0/10 (0)	0/24 (0)	0/6 (0)	1.0
Family history major, n (%)	11/11 (100)	28/28 (100)	7/22 (32)	<0.001
Family history minor, n (%)	0/11 (0)	0/28 (0)	15/22 (68)	<0.001
Total major score, median [IQR]	3 [2 to 3]	1 [1 to 1]	0 [0 to 1]	<0.001
Total minor score, median [IQR]	2 [1 to 2]	0 [0 to 0.5]	1 [1 to 1]	<0.001
Definite TFC, n (%)	11/11 (100)	2/28 (7)	0/22 (0)	<0.001
Borderline TFC, n (%)	0/11 (0)	7/28 (25)	2/22 (9)	0.113

ARVC indicates arrhythmogenic right ventricular cardiomyopathy; CMR, cardiac magnetic resonance imaging; TFC, Task Force Criteria.