Table 4.

New Cardiology‐Specific Recommendations for Tuberous Sclerosis Complex

Cardiac rhabdomyomas remain a major diagnostic criterion

Echocardiogram at the time of diagnosis If fetal diagnosis, then serial observation and at least 1 postnatal echocardiogram Surveillance studies until regression demonstrated

Electrocardiogram at the time of diagnosis Surveillance studies every 3 to 5 years Holter monitor as indicated for appropriate signs and symptoms

Cardiology consultation at time of diagnosis Ongoing cardiology surveillance as indicated Medical and surgical intervention as indicated Referral to genetics and neurology when cardiology makes initial diagnosis Pediatric to adult transition plan with ongoing cardiology surveillance