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. 2015 Feb 24;9:47. doi: 10.3389/fncel.2015.00047

Figure 7.

Figure 7

Spatiotemporal dynamics of PC firing during complex bursting. The panels on top show screenshots of PC membrane potential observed at different times during complex bursting (membrane potential is color-coded onto model morphology). Arrows point to the corresponding time on the traces representing membrane potential recorded in distal dendrites, soma and 3rd RN. By looking at the sequence of screenshots from left to right it appears that, at the end of the spike burst, the PC model depolarizes starting from distal dendrites before the depolarization invades the whole dendritic tree. A large Ca spike is the most relevant depolarizing event in terminal dendrites, while fast Na spikes are most evident in AIS. In the 3rd RN, there is no firing pause during the dendritic Ca spike.