TABLE 1.

Incidence, Severity, and Duration of Spontaneous Seizures in 2- to 3-Month-Old Scn1a^RX/+ Mice and Littermates with 2 or No Tau Alleles

Genotype
Scn1a	Tau	Mice, No.	Hours of EEG Recording	Mice with Seizures, %a	Seizure Severityb	Seizure Duration, sa
+/+	+/+	9	216	0	N/A	N/A
+/+	−/−	7	168	0	N/A	N/A
RX/+	+/+	21	1,169	43	4.5 ± 0.9	34.1 ± 10.0
RX/+	−/−	25	1,233	16	4.3 ± 1.0	33.6 ± 9.2

^aDetermined by EEG and observation of mouse behavior.

^bSeizure severity was scored as described in Materials and Methods.

^cp < 0.05 versus Scn1a^RX/+/Tau^+/+ (Fisher exact test).

EEG = electroencephalogram; N/A = not applicable.