Figure 6. LRRK2 interactors enrichment for “GO cell component” and “GO biological process” terms.

The LRRK2 filtered interactome is shown after WebGestalt enrichment analysis. The enriched GO terms were grouped in: transport/localization, cell organization, regulation of kinase activity, cytosol, vesicles, cytoskeleton and cell projections. Every protein in the filtered interactome was connected to the GO term groups it has participated toward the enrichment. In the table the 7 groups are listed in columns (A–G) and rows (1–7). The percentage of proteins from the LRRK2 interactome that contributed toward the enrichment of the GO term group listed in the row and that were also reported in the GO term group reported in the column was calculated (intersection between the group in the row and the group in the column). In the last row of the table the percentage of the proteins that contributed toward the enrichment of each GO term group was calculated against the total number of LRRK2 interactors (i.e., 62 proteins). Cells discussed in the text are highlighted.