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. 2015 Feb 24;3:18. doi: 10.3389/fbioe.2015.00018

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Copyright © 2015 Nigita, Alaimo, Ferro, Giugno and Pulvirenti.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Receiver operating characteristic curve (ROC) computed for the two prediction algorithms. We also provide a ROC curve for a variant of our algorithm (AIRlINER 4 nt), which takes into account only the flanking region of 4 nt around an adenosine. Such a curve is useful to compare the performance with our algorithm using the same flanking region. AIRlINER shows an average area under the ROC curve (AUC) equal to 0.7466, while InosinePredict gets an AUC of 0.5072. AIRlINER 4 nt has an AUC of 0.7464.