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. 2015 Feb 19;15:74. doi: 10.1186/s12879-015-0799-x

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© Ferraz et al.; licensee BioMed Central. 2015

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Ex vivo analysis of total CD8 ⁺ T-lymphocyte frequency and apoptosis in human cutaneous leishmaniasis. (A) Total CD8⁺ T lymphocytes; (B) Effector CD8⁺ T lymphocytes; (C) Apoptotic-total CD8⁺ T lymphocytes; (D) Apoptotic-effector CD8⁺ T lymphocytes. HS - healthy subjects (n = 18); PBT – patients before treatment (n = 8); PDT - patients during treatment (n = 14); PAT - patients after treatment (n = 11). Statistical analyses were performed by Mann Whitney Test. The bars represent the mean ± standard error. Results were considered significant with P < 0.05 - ^*(P < 0.05) **(P < 0.01) ***(P < 0.001).