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i.r. challenge with the clade C SHIV-405c and SHIV-459c stocks in rhesus monkeys. Six animals were challenged once with 1 ml of undiluted SHIV-405c (n = 3) (A) or SHIV-459c (n = 3) (B) stocks by the i.r. route. The upper panel shows plasma viral loads, and the lower panel shows the percentage of CD4+ T cells in peripheral blood. The dotted line reflects the limit of detection of the assay (50 RNA copies/ml).
