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. Author manuscript; available in PMC: 2015 Feb 24.
Published in final edited form as: Nanomedicine (Lond). 2014 Mar 19;9(3):469–485. doi: 10.2217/nnm.14.4

Table 1.

Magnetic nanoparticle synthesis methods.

Method Temperature Simplicity Size distribution Yield Coatings
Co-precipitation Room temperature Simple, minutes Narrow High, scalable Dextran, chitosan, other polymers
Hydrothermal synthesis High Simple, high pressure, days Very narrow Medium, automated Silicon, titanium, polyethylene glycol
Microemulsion Room temperature Complicated, hours Narrow Low Lipids, polymers
Thermal decomposition High Complicated, inert conditions, hours–days Very narrow High, scalable Chitosan, other polymers, proteins, surfactants

Parameters summarized in [2,30]