Fig. 1.

Two weeks of exposure to hypoxia do not significantly alter mitochondrial shape and content in the right ventricle (RV) and left ventricle (LV). A–D: representative electron micrographs of control (CO) LV (A), CO RV (B), hypobaric hypoxia (HH) LV (C), and HH RV (D). E: expression of mitochondrial electron transport chain complexes was assessed by immunoblotting, using an antibody against one subunit of each complex; n = 10 experiments in each condition. F: mitochondrial DNA copy number was assessed by real-time PCR and expressed relative to a nuclear DNA housekeeping gene; n = 6 in each condition.