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. 2014 Oct 17;308(2):L199–L207. doi: 10.1152/ajplung.00237.2014

Fig. 3.

Fig. 3.

HER2 activation is associated with β-catenin-E-cadherin dissociation. A: NuLi-1 cells grown at ALI were stimulated with NRG-1 (20 nM) with and without lapatinib, and E-cadherin immunoprecipitation followed by β-catenin and E-cadherin Western blotting was performed. B: densitometry of E-cadherin/β-catenin association by coimmunoprecipitation in NuLi-1 cells treated with and without lapatinib relative to corresponding control. C: NHBE cells grown at ALI were treated with NRG-1 and lapatinib followed by immunoprecipitation for E-cadherin and Western blotting for E-cadherin and β-catenin. D: densitometry of E-cadherin/β-catenin association by coimmunoprecipitation in NHBE cells treated with and without lapatinib relative to corresponding control. Data are presented as means ± SE. *P < 0.05, n ≥ 3.