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. 2015 Feb 12;14(Suppl 1):37–44. doi: 10.4137/CIN.S24657

Figure 4.

Figure 4

The comparisons of tumor/normal mixtures and normal cell lines (HCC1143_BL and HCC1954_BL). (A) The 100% normal is a subset of reads in normal cell line (HCC1143_BL or HCC1954_BL) with the coverage 30×. Tumor/normal mixtures consist of different combinations of reads from normal 30× and tumor cell line (HCC1143_T or HCC1954_T). (B) and (C) The comparisons of ALUs insertions on mixtures and normal cell lines. The falling rate of ALUs in the intersections is milder than the falling rate of normal reads in mixtures, which means that TANGRAM is indeed affected by the contamination but not severely.