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. 2015 Feb 12;14(Suppl 1):37–44. doi: 10.4137/CIN.S24657

Figure 6.

Figure 6

The comparisons of tumor/normal/subclone mixtures and normal cell lines (HCC1143_BL and HCC1954_BL). (A) In all, ∼500 novel SNVs and ∼200 novel SVs are spiked into each subclone, combining with normal and tumor reads to create a subclone spike-in mixture. (B) and (C) The comparisons of ALUs insertions on mixtures and normal cell lines. We infer that ALUs are not included in subclonal mutations because we do not see more ALUs as more subclonal mutations spiked in (from the left-hand to the right-hand sides).