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. Author manuscript; available in PMC: 2015 Aug 1.
Published in final edited form as: Medchemcomm. 2014 Aug;5(8):1138–1142. doi: 10.1039/C4MD00095A

Table 5.

Anticancer and bacterial activity (μM) for the mezzettiaside R1 ester disaccharide analogues.

R R1 MICa IC50b
B. subtilis H460
Mezze-10 Ac H >128 >500
Mezze-11 Ac Ac >128 15
15 Ac n-PrCO >128 32
16 Ac t-BuCO >128 141
17 Ac i-PrCO >128 47
18 Ac i-BuCO >128 79
a

All values of MIC and IC50 (μM) are an average of at least three independent experiments.

b

All values of MIC and IC50 (μM) are an average of at least three independent experiments.