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. 2014 Dec 31;10:961. doi: 10.1186/s12917-014-0303-7

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© Dhiyaaldeen et al.; licensee BioMed Central. 2014

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Immunohistochmical analysis of TGF-β protein expression in gastric tissue of rat induced with indomethacin. (A) Section shows normal mucosal area and express regulated of TGF-β (red arrow). (B) Section of ulcerated stomach tissue ashowed down-regulation of TGF-β almost non-existent in injured area (white arrow). Sections (C, D and E) that pre-treated with 50, 100 mg/kg of HPTP and 20 mg/kg of omeprazole respectively found the up-regulation of TGF-β (red arrows) (magnification 20x).