Table 3.
Distribution of anatomic features in cases with tetralogy of Fallot by 22q11.2 deletion status
| Characteristic | Without 22q11 deletion No. (%) |
With 22q11 deletion No. (%) |
P value* |
|---|---|---|---|
| TOF valve anatomy | |||
| Pulmonary stenosis | 392 (74.8) | 47 (58.7) | 0.01 |
| Pulmonary atresia | 107 (20.4) | 29 (36.2) | |
| Absent pulmonary valve | 25 (4.7) | 4 (5.0) | |
| Aortic arch anomaly | |||
| No | 350 (65.2) | 32 (39.0) | <0.001 |
| Yes | 187 (34.8) | 50 (61.0) | |
| Multiple aortopulmonary collateral arteries | |||
| No | 425 (84.7) | 53 (69.7) | 0.001 |
| Yes | 77 (15.3) | 23 (30.3) | |
| Discontinuous branch pulmonary arteries | |||
| No | 485 (95.5) | 72 (91.1) | 0.10 |
| Yes | 23 (4.5) | 7 (8.9) |
Chi-square analysis