Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
The clinical course of active EAE is attenuated in CPN−/− mice compared to wild type mice. Active EAE was induced with MOG35-55 peptide and clinical signs scored for 30 days as described in Materials and Methods. CPN−/− mice (n=10) have significantly reduced disease from day 10 through 30 (p<0.001, Wilcoxon rank sum test) compared to wild type mice (n=13). Results shown are the daily mean clinical score for wild type and CPN−/− mice from four experiments.
