Th1 immune responses exaggerate urinary excretion of nephrin in Ang II-dependent hypertension. A, Systolic and B, Diastolic blood pressures measured by radiotelemetry in the experimental groups at baseline (“pre”) and during chronic Ang II infusion. Wild-type (WT), circles. T-bet KO (KO), squares. n = 7 per group. C, Urinary nephrin excretion (μg/24hrs) after 25 days of Ang II.