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. 2015 Feb 18;19(1):43. doi: 10.1186/s13054-015-0775-2

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© Liu et al.; licensee BioMed Central. 2015

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Description of reference points used for calculation of respiratory variables. Reference points are indicated for calculating peak airway pressure (Paw_pk), change in esophageal pressure (Pes) from onset of electrical activity of the diaphragm (EAdi) to peak (nadir) (ΔPes), change in transpulmonary pressure (Ptp) from onset of EAdi to peak (ΔPtp), peak EAdi (EAdi_pk) and inspiratory tidal volume (Vt_insp). Neural inspiratory period (Ti) and total breath time (Ttot) are indicated at bottom. Breathing frequency (Fb) was calculated as 60/Ttot.