Table 3.
Available Data on Outcomes After Simultaneous and Staged HCR Strategies
| Author, Year (Ref) | No. | PCI Strategy | CABG Strategy |
In-Hospital Mortality |
In-Hospital Stroke |
Reoperation For Bleeding |
In-Hospital LIMA Patency |
Hospital Stay (Days) |
F/U Period |
Survival | Freedom From MACCEa |
TLR |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Simultaneous HCR | ||||||||||||
| Kon, 2008 [17] | 15 | DES (100) | MIDCAB | 0 | 0 | 0 | 100 | 3.7 ± 1.4 | 12 mo | 100 | 93 | 6.7 |
| Bonatti, 2008 [45] | 5 | DES (100) | TECAB | 0 | 0 | 0 | 100 | 6 (5-7) | 6 mo | 100 | 100 | 0 |
| Kiaii, 2008 [30] | 58 | DES (90), BMS (10) | Endo-ACAB | 0 | 1.7 | 5.2 | 93 | 4.3 ± 1.4 | 20 mo | 100 | 100 | 2.3 |
| Reicher, 2008 [31] | 13 | DES (100) | MIDCAB | 0 | 0 | 0 | 100 | 3.6 ± 1.5 | 14 | 100 | 92 | 7.6 |
| Zhao, 2009 [16] | 112 | DES (84), BMS (8) | On-pump CABG (90), OPCAB (22) | 2.7 | 1.8 | 2.7 | 93 | 6 (1-97) | — | — | — | — |
| Hu, 2011 [28] | 104 | DES (98), BMS (2) | MIDCAB | 0 | 0 | 3.8% | 96 | 8.2 ± 2.6 | 18 | 100 | 99 | 1.9 |
| Staged HCR: PCI followed by CAB | ||||||||||||
| Lewis, 1999 [56] | 14 | BMS (100) | MIDCAB | 0 | 0 | 0 | 100 | 3.4 ± 2.1a | 1-14 mo | 100 | 90 | 9.6 |
| Lee, 2004 [57] | 6 | BMS (100) | MIDCAB | 0 | 0 | 0 | — | 6 (4-7) | 12 mo | 100 | — | 16 |
| Gilard, 2007 [44] | 70 | BMS (100) | On-pump CABG | 1.4 | 0 | 0 | 100 | — | 33 mo | 98.6 | 96 | 2.3 |
| Staged HCR: CAB followed by PCI | ||||||||||||
| Isomura, 2000 [58] | 37 | PTCA (100) | MIDCAB | 0 | 0 | — | 100 | — | 0-24 mo | 97.3 | 92 | 8.1 |
| Wittwer, 2000 [59] | 35 | PTCA (70), BMS (30) | MIDCAB | 0 | 0 | 0 | 100 | 7.5 ± 4.1 | — | — | — | — |
| Cisowksi, 2002 [41] | 50 | PTCA (22), BMS (78) | Endo-ACAB | 0 | 0 | 2.8 | 100 | 4.4 ± 1.7 | 12 mo | 100 | 88 | 10 |
| Riess, 2002 [39] | 57 | PTCA (7), BMS (93) | MIDCAB | 0 | 0 | 0 | 98 | 5.7 ± 1.8 | 24 mo | 98.2 | 98 | 14 |
| Gao, 2009 [35] | 10 | BMS (67), DES (33) | Endo-ACAB (6), TECAB (4) | 0 | 0 | 0 | 100 | — | 5 mo | 100 | 100 | 0 |
| Delhaye, 2010 [46] | 18 | DES (100) | OPCAB (5), On-pump CABG (13) | 0 | 0 | 0 | 100 | 10 (10-11.2) | 12 mo | 100 | 89 | 12 |
In the case series of Lewis et al [56], PCI and MIDCAB occurred within 1 day, but took place in 2 stages.
BMS = bare-metal stents; CABG = coronary artery bypass grafting; CAD = coronary artery disease; DES = drug-eluting stent; Endo-ACAB = endoscopic atraumatic coronary artery bypass; F/U = follow-up; HCR = hybrid coronary revascularization; LIMA = left internal mammary artery; MACCE = major adverse cardiac and cerebrovascular events; MIDCAB = minimally invasive direct coronary artery bypass; mo = months; OPCAB = off pump coronary artery bypass; PCI = percutaneous coronary intervention; PTCA = percutaneous transluminal coronary angioplasty; TLR = target lesion revascularization.