Table 1.
Baseline Characteristics of Donors to Recipients of Single-Lung Transplantation, Stratified by Whether One or Both Lungs Were Subsequently Transplanted
| Variablea | All donors (n = 7,232) |
Single donated (n = 4,103) |
Both donated (n = 3,129) |
p-value |
|---|---|---|---|---|
| Age, years | 29 (20, 43) | 28 (20, 43) | 30 (20, 44) | <0.001 |
| Sex | 0.426 | |||
| Female | 2,547 (35.2) | 1,429 (34.8) | 1,118 (35.7) | |
| Male | 4,685 (64.8) | 2,674 (65.2) | 2,011 (64.3) | |
| BMI, kg/m2 | 24 (21.5, 27) | 24 (21.6, 27.1) | 23.9 (21.5, 26.9) | 0.425 |
| BSA, m2 | 1.9 (1.7, 2) | 1.9 (1.7, 2) | 1.9 (1.7, 2) | 0.64 |
| Ethnicity | 0.003 | |||
| White | 5,104(70.6) | 2,872 (70) | 2,232 (71.3) | |
| Black | 1,126 (15.6) | 611 (14.9) | 515 (16.5) | |
| Asian | 815 (11.3) | 503 (12.3) | 312 (10) | |
| Other | 187 (2.6) | 117 (2.9) | 70 (2.2) | |
| Tobacco abuse | 4,791 (66.2) | 2,687 (65.5) | 2,104 (67.2) | <0.001 |
| Drug use | 1,722 (23.8) | 965 (23.5) | 757 (24.2) | 0.523 |
| Diabetes | 256 (3.5) | 147 (3.6) | 109 (3.5) | 0.871 |
| Tattoos | 0.009 | |||
| No | 3,384 (46.8) | 1,859 (45.3) | 1,525 (48.7) | |
| Yes | 1,136 (15.7) | 677 (16.5) | 459 (14.7) | |
| Unknown | 2,712 (37.5) | 1,567 (38.2) | 1,145 (36.6) | |
| PaO2, mm Hg | 431 (332, 497) | 409 (302.5, 480) | 455 (376, 513) | <0.001 |
| Bilirubin, g/dl | 0.8 (0.5, 1.2) | 0.8 (0.5, 1.2) | 0.8 (0.5, 1.2) | 0.579 |
| AST, g/dl | 44 (28, 75) | 45 (29, 79) | 42 (27,70.2) | <0.001 |
| ALT, g/dl | 30 (20, 51) | 31 (20, 55) | 29 (19,46) | <0.001 |
| CMV status | <0.001 | |||
| Negative | 2,999 (41.5) | 1,646 (40.1) | 1,353 (43.2) | |
| Positive | 4,188 (57.9) | 2,421 (59) | 1,767 (56.5) | |
| Unknown | 45 (0.6) | 36 (0.9) | 9 (0.3) | |
| Cause of death | <0.001 | |||
| Anoxia | 474 (6.6) | 285 (6.9) | 189 (6) | |
| CNS Tumor | 61 (0.8) | 30 (0.7) | 31(1) | |
| CVA/stroke | 2,396 (33.1) | 1,243 (30.3) | 1,153 (36.8) | |
| Head trauma | 3,730 (51.6) | 2,186 (53.3) | 1,544 (49.3) | |
| Other | 561 (7.8) | 352 (8.6) | 209 (6.7) | |
| Unknown | 10 (0.1) | 7 (0.2) | 3(0.1) | |
| ECD donor | 489 (7.9) | 295 (8.5) | 194 (7) | 0.036 |
| Pulmonary infection | 1,573 (21.8) | 943 (23) | 630 (20.1) | 0.004 |
ALT, alanine aminotransferase; AST, aspartate aminotransferase; BMI, body mass index; BSA, body surface area; CMV, cytomegalovirus; CNS, central. nervous system; CVA, cerebrovascular accident; ECD, extended criteria donor; PaO2, partial pressure of arterial oxygen.
a
Continuous variables are expressed as median (interquartile range) and categoric variables as number (%).