Panel A. In traditional tissue engineering approaches, a first procedure removes tissue biopsies. Autologous cells are isolated, seeded on a matrix and incubated in a bioreactor under conditions where new tissue is formed. The graft is implanted into the patient in a second procedure.
Panel B. Expedited approaches require a single percutaneous, minimally invasive, or intra-operative procedure.
From reference 1, as modified from reference 5, with permission.