Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Potential mechanisms of action for various hypoxia targeted therapies. The number of stars (ranging from 1 star = least effect to 4 stars = most effect) represent the role and degree of each mechanistic process i.e indirect effect due to tissue oxygen level or direct effect on hypoxic cells.
| Approach | Oxygen Level | Hypoxic Cells |
|---|---|---|
| XRT | ** | * |
| Neutrons | **** | * |
| HBO, Carbogen | **** | * |
| Fractionation | *** | ? |
| Radiosensitizers | - | *** |
| Hypoxic Cell Cytotoxins | - | **** |
