Table 2.
Average morphometric data of sural nerves fascicles from the four experimental groups: normotensive Wistar rat control group (WR), normotensive Wistar rat chronically induced diabetes group (WR + STZ), spontaneously hypertensive rat group (SHR), spontaneously hypertensive rat chronically induced diabetes group (SHR + STZ)
| WR | WR + STZ | SHR | SHR + STZ | |
|---|---|---|---|---|
| Fascicular area (μm2) | 76963 ± 4361 | 64739 ± 3732 | 50018 ± 2047 | 42670 ± 2345*+ |
| Fascicular diameter (μm) | 202 ± 24 | 169 ± 17 | 153 ± 10 | 156 ± 11 |
| Myelinated fiber number | 1079 ± 82 | 1039 ± 50 | 849 ± 28*+ | 767 ± 28*+ |
| Myelinated fiber density (number of fibers/μm2) | 13994 ± 601 | 16894 ± 1113 | 17206 ± 391*+ | 18471 ± 684*+ |
| Schwann cell nucleus number | 60 ± 5 | 66 ± 4 | 51 ± 2 | 28 ± 2*+# |
| Schwann cell nucleus density (number of nucleus/μm2) | 789 ± 60 | 1094 ± 103 | 1055 ± 60*+ | 670 ± 77+# |
| Capillary occupancy (%) | 0.90 ± 0.18 | 0.91 ± 0.17 | 0.43 ± 0.08 | 0.27 ± 0.06*+ |
*indicates significant difference compared to Normotensive Wistar rat (WR) group; + indicates significant difference compared to Normotensive Wistar rat with chronic induced diabetes (WR + STZ) group; # indicates significant difference compared to Spontaneously hypertensive rat (SHR) group.