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. Author manuscript; available in PMC: 2015 Mar 21.
Published in final edited form as: Chem Commun (Camb). 2014 Mar 21;50(23):3018–3020. doi: 10.1039/c3cc47862a

Figure 2.

Figure 2

Detection of mutated gene using modified AuNPs and total mRNA extracts (5.5 ng/μL) of different cell lines. C918 expresses wild type GNAQ, OMM1.3 expresses mutated GNAQ and mRNA from mouse liver that do not contain the GNAQ gene. The nanoparticles are designed to detect the mutated GNAQ gene present in the OMM1.3 cell line. The drop in absorbance in the blue bar is due to the presence of the mutated GNAQ gene. Values obtained as an average of three experiments.