Table 1. Comparison of body weight, muscle weight and centronucleation in FVB and mdx/FVB mice.
Data shown as mean ± standard error of mean. a, significantly different from the 3-m-old FVB control group; b, significantly different from the 6-m-old FVB control group.
Abbreviations: EDL, extensor digitorum longus; CSA, cross sectional area; TA, tibialis anterior; CN, central nucleation.
Sample size: Body weight n=11-14 for FVB, n=11-19 for mdx/FVB; EDL weight/CSA n=14-24 for FVB, n=12-18 for mdx/FVB; TA weight/CSA n=8-10 for FVB, n=8-9 for mdx/FVB; CN analysis n= 10-11 for each strain.
| FVB | mdx/FVB | |||
|---|---|---|---|---|
| 3-m-old | 6-m-old | 3-m-old | 6-m-old | |
| Body weight (g) | 28.67±0.60 | 32.52±0.44 | 34.06±0.58a | 39.19±1.20b |
| EDL weight (mg) | 11.08±0.27 | 12.36±0.16 | 14.03±0.14a | 13.41±0.19b |
| EDL CSA (mm2) | 1.81±0.04 | 1.95±0.03 | 2.13±0.05a | 2.07±0.04b |
| TA weight (mg) | 52.92±1.45 | 65.38±1.04 | 62.24±3.01a | 73.99±2.10b |
| TA CSA (mm2) | 5.63±0.15 | 6.90±0.12 | 6.08±0.29 | 7.29±0.14b |
| Central nucleation (%) | 0.28±0.15 | 0.19±0.03 | 65.80±1.44a | 70.77±0.82b |