Figure 7.

Pharmacology implicates α6* nAChRs in efferent-mediated excitation of CD afferents. A, B, Average response histogram of a CD and BT afferent to the standard efferent shock train before and during the application of 2 μm α-CtxMII, respectively. C, D, Average response histogram of a CD and BM afferent to the standard efferent shock train before and during application of 300 nm bPiDDB, respectively. Efferent shock trains (20 shocks at 200/s, black bar at t = 0) were repeated every 3 s and all histograms were based on ≥20 shock train presentations.