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. 2015 Feb 24;10(2):e0117695. doi: 10.1371/journal.pone.0117695

Fig 3. Inhibition of C. albicans filamentation by honokiol and magnolol in different hyphal-inducing media.

Fig 3

(A-G) Colonies were grown on solid spider media agar plates overlaid with vehicle (control), magnolol, or honokiol. Images of colony edges were obtained using a microscope. (A) Solvent controls; (B) 4 μg/mL of honokiol; (C) 8 μg/mL of honokiol; (D) 16 μg/mL of honokiol; (E) 4 μg/mL of magnolol; (F) 8 μg/mL of magnolol; (G) 16 μg/mL of magnolol. (H-J) Honokiol and magnolol inhibited C. albicans filamentation induced on RPMI1640, GlcNAc, or FBS YPD medium. C. albicans CASA1 (1 × 106 cells/mL) with honokiol, or magnolol was incubated in (H) RPMI1640, (I) GlcNAc, or (J) 10% FBS YPD medium at 37°C for 4 h. Bars represent means ± S.E.M. **P < 0.01. (K) representative images of C. albicans cells obtained using a fluorescent microscope. Honokiol and magnolol were added at a concentration of 16 μg/mL.