Table 3. Mixed linear models modeling eGFR change, by sex.
eGFR, men | eGFR, women | log(eGFR), men | log(eGFR), women | |
---|---|---|---|---|
Log leptin | -0.732 (-1.836, 0.371) | -1.664 (-2.806, -0.523) | -1.055 (-2.56, 0.474) | -2.47 (-4.074, -0.8398) |
Age | -0.755 (-0.843, -0.666) | -0.716 (-0.806, -0.625) | -0.934 (-1.058, -0.81) | -0.904 (-1.036, -0.773) |
Waist to hip ratio | 3.744 (-12.66, 20.15) | -4.603 (-17.562, 8.356) | 5.451 (-15.9, 32.222) | -6.083 (-22.1, 13.22) |
Smoking | -0.436 (-1.173, 0.301) | 0.436 (-0.529, 1.401) | -0.493 (-1.528, 0.554) | 0.587 (-0.837, 2.031) |
Systolic blood pressure | 0.052 (-0.001, 0.106) | 0.07 (0.014, 0.126) | 0.084 (0.01, 0.157) | 0.121 (0.04, 0.2017) |
Hypertension | 2.184 (-0.95, 5.318) | 2.632 (-0.532, 5.796) | 3.752 (-0.714, 8.419) | 2.535 (-2.096, 7.3853) |
Diabetes | -1.934 (-6.327, 2.459) | 1.079 (-3.677, 5.834) | -3.083 (-8.881, 3.084) | 1.204 (-5.589, 8.4862) |
Triglycerides | -2.346 (-4.555, -0.137) | 0.13 (-2.235, 2.494) | -2.476 (-5.421, 0.561) | 0.121 (-3.259, 3.6201) |
LDL cholesterol | -0.047 (-0.073, -0.021) | -0.042 (-0.066, -0.018) | -0.067 (-0.103, -0.03) | -0.056 (-0.091, -0.021) |
HDL cholesterol | 0.011 (-0.069, 0.091) | -0.026 (-0.095, 0.043) | 0.047 (-0.065, 0.158) | -0.019 (-0.119, 0.0818) |
C-reactive protein | 0.469 (-0.51, 1.448) | -0.269 (-1.244, 0.706) | 0.928 (-0.43, 2.305) | -0.131 (-1.535, 1.2922) |
IL-6 | 0.71 (-0.923, 2.343) | 1.302 (-0.218, 2.823) | 0.5 (-1.74, 2.791) | 1.812 (-0.395, 4.0681) |
TNF | -0.568 (-1.908, 0.772) | -1.545 (-3.052, -0.038) | -0.642 (-2.465, 1.215) | -2.601 (-4.704, -0.451) |
Physical activity (high vs. low) | -0.641 (-2.26, 0.978) | 0.56 (-1.413, 2.533) | -0.568 (-2.759, 1.672) | 1.127 (-1.705, 4.041) |
Use of ACEI/ARB | -0.401 (-4.501, 3.699) | 0.081 (-3.511, 3.674) | -0.627 (-6.192, 5.268) | -0.428 (-5.521, 4.94) |