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. 2015 Feb 13;15:57. doi: 10.1186/s12879-015-0793-3

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© Merseguel et al.; licensee BioMed Central. 2015

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Analysis of nucleotide sequence variation of rDNA ITS in medically important Candida spp. Polymorphic sites in ITS1-5.8S-ITS2 rDNA were evaluated along the total sequence lengths for the following species for the assessment of the percentage of nucleotide variation per site, for which the sequences of the clinical strains were compared with the sequence of the reference or type strain for each species: (A) C. albicans (447 bp, 78 sequences), (B) C. tropicalis (437 bp, 41 sequences), (C) C. glabrata (803 bp, 48 sequences), (D) C. parapsilosis (sensu stricto) (430 bp, 35 sequences), (E) C. orthopsilosis (426 bp, 32 sequences), and (F) M. guilliermondii (516 bp, 22 sequences).