Skip to main content
. Author manuscript; available in PMC: 2016 Jan 1.
Published in final edited form as: Semin Cell Dev Biol. 2014 Oct 8;0:26–34. doi: 10.1016/j.semcdb.2014.09.027

Figure 1. Monomeric IDP structural features and dynamics.

Figure 1

Figure top depicts the principle of diffusion smFRET and FCS detection. Data Panel A is adapted from Crick et al. Proc. Natl. Acad. Sci. (2006) 103:16764, and shows the scaling of diffusion times vs. chain length as measured by FCS. Panels B and C are from Mukhopadhyay et al. Proc. Natl. Acad. Sci. (2007) 104:2649, which show evidence for rapid IDP fluctuations via a relatively narrow smFRET peak on FRET efficiency vs. population (number of events) histogram (B) and rapid-timescale FCS decays (C).