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. Author manuscript; available in PMC: 2016 Mar 1.
Published in final edited form as: Osteoarthritis Cartilage. 2014 Nov 29;23(3):405–413. doi: 10.1016/j.joca.2014.11.021

Figure 6. Cellular connectivity was observed in the load-bearing regions of articular cartilage following optical clearing.

Figure 6

(A) Chondrocytes in the load-bearing regions of lateral condyles showed connectivity and protrusions (white arrows) compared to non-load-bearing regions. Cartilage was stained for SZP/lubricin/PRG4 (red), actin (green), and DNA (blue). Scale bars = 20 μm. (B) Three-dimensional renderings of chondrocytes confirm cell connectivity. Bounding box dimensions = 40×40×20 μm3 (l×w×h).