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. Author manuscript; available in PMC: 2016 Mar 1.
Published in final edited form as: Gastroenterology. 2014 Dec 6;148(3):537–546.e4. doi: 10.1053/j.gastro.2014.11.020

Figure 2.

Figure 2

Upper panel: Relationship of kcal intake at prior ad-libitum meal and kcal intake in response to randomized treatment; note that there are significant associations in both treatment groups. Lower panel: Association of change in body weight (in response to randomized treatment with placebo or phentermine-topiramate-ER) and kcal intake at prior ad-libitum meal. Note the kcal intake at baseline prior to treatment is associated with the degree of weight loss on treatment with phentermine-topiramate-ER with no observed effect with placebo treatment. This is illustrated by p=0.029 for the drug treatment interaction.