Table 2.
AgNOR parameters in the global analysis of all DRN subregions in paranoid versus residual schizophrenia patients and controls
| Parameter | C, n = 28 | P, n = 8 | R, n = 9 | P values | P values | P values |
|---|---|---|---|---|---|---|
| Mean ± SD | Mean ± SD | Mean ± SD | P versus R | P versus C | R versus C | |
| Nuclear area in µm2 | 108.8 ± 28.5 | 107.4 ± 22.7 | 112.9 ± 27.4 | n.s. | n.s. | n.s. |
| AgNOR area in µm2 per nucleus | 19.01 ± 2.39 | 19.27 ± 2.12 | 22.9 ± 4.04 | 0.028 | n.s. | 0.002 |
| Number of AgNORs per nucleus | 1.06 ± 0.06 | 1.03 ± 0.03 | 1.07 ± 0.07 | n.s. | n.s. | n.s. |
| Relative AgNOR area | 0.191 ± 0.029 | 0.189 ± 0.020 | 0.230 ± 0.034 | 0.030 | n.s. | 0.007 |
C controls, P paranoid schizophrenia, R residual schizophrenia, n.s. non-significant, n number of cases, SD standard deviation, P values t tests P values (with Bonferroni correction for multiple comparisons; significant values are in bold)